By Neal M. Davies, Jaime A. Yáñez, Basil Roufogalis
SETS FORTH A FRAMEWORK FOR THE research AND learn OF FLAVONOIDS
More and extra supplements include flavonoids. those items tend to be seen as nutrients instead of drug items via regulatory enterprises and hence no longer subjected to rigorous medical trials ahead of they're advertised to most of the people. therefore, using flavonoid-containing vitamins provides a possible public overall healthiness chance. From discovery to healing software, this ebook is a entire advisor to either achiral and chiral flavonoids, permitting researchers to accomplish crucial preclinical and medical pharmacokinetics experiences which will make sure the efficacy of flavonoids advertised for healing use. additionally, the e-book examines the protection and toxicology of flavonoids in addition to flavonoid-drug interactions.
With contributions from a multidisciplinary workforce of top researchers, Flavonoids Pharmacokinetics reports and synthesizes the newest learn findings and effects from preclinical and scientific reports. The publication starts off with a complete assessment of polyphenols and flavonoids. subsequent, the ebook covers:
- Methods of study of achiral flavonoids
- Preclinical pharmacokinetic of flavonoids
- Toxicology and protection of flavonoids
- Methods of study for chiral flavonoids
- Clinical pharmacokinetics of flavonoids
- Flavonoids and drug interactions
Throughout the publication, the authors supply examples that exhibit using pharmacokinetics suggestions through the preclinical and medical drug improvement process.
Flavonoid Pharmacokinetics is written for pharmaceutical, nutrition, and dietary scientists and scholars, delivering the instruments they should completely research and attempt flavonoids and flavonoid-containing supplementations to make sure their defense and efficacy.
Chapter 1 Polyphenols and Flavonoids: an summary (pages 1–69): Jaime A. Yanez, Connie M. Remsberg, Jody okay. Takemoto, Karina R. Vega?Villa, Preston okay. Andrews, Casey L. Sayre, Stephanie E. Martinez and Neal M. Davies
Chapter 2 research of Flavonoids via Chromatography (pages 71–115): Jody okay. Takemoto, Stephanie E. Martinez and Neal M. Davies
Chapter three Chiral tools of Flavonoid research (pages 117–159): Jaime A. Yanez, Casey L. Sayre, Stephanie E. Martinez and Neal M. Davies
Chapter four Preclinical Pharmacokinetics of Flavonoids (pages 161–193): Jaime A. Yanez, Casey L. Sayre and Neal M. Davies
Chapter five medical Pharmacokinetics of Flavonoids (pages 195–247): Casey L. Sayre, Karen D. Gerde, Jaime A. Yanez and Neal M. Davies
Chapter 6 Toxicology and security of Flavonoids (pages 249–280): Stephanie E. Martinez, Neal M. Davies and Jonathan okay. Reynolds
Chapter 7 Flavonoids and Drug Interactions (pages 281–319): Jaime A. Yanez, Nagendra V. Chemuturi, Scott W. Womble, Casey L. Sayre and Neal M. Davies