Download Calcium Signalling and Disease: Molecular Pathology of by M.J. HAYES, R.E. LONGBOTTOM, M.A. EVANS, S.E. MOSS (auth.), PDF

By M.J. HAYES, R.E. LONGBOTTOM, M.A. EVANS, S.E. MOSS (auth.), Ernesto Carafoli, Marisa Brini (eds.)

This subject is a brand new access within the sector of mobile calcium signaling: but, it now spans the full region, with discoveries that conceal either genetic and purchased pathologies, even delivering glimpses towards remedy.

Cellular calcium homeostasis, and therefore calcium signalling, is especially regulated via membrane intrinsic proteins and calcium sensor proteins. either periods can be eager about pathological techniques that have an effect on either human and animals, starting from universal and significant ailments (e.g. migraine, diabetes, epilepsia, manic melancholy, infertility, a variety of different types of melanoma, Alzheimer’s ailment, muscular dystrophy) to infrequent genetic stipulations (e.g., a couple of genetic center stipulations, autoimmune retinopathies, evening blindness, hereditary amyloid polyneuropathy, malignant hyperthermia, cerebellar ataxia, atherothrombotic disease).

Clearly, the subject has now turn into not just very huge, but additionally very stimulating. Its huge serious insurance is probably going to ultimately stimulate fruitful interdisciplinary discussions.

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Extra resources for Calcium Signalling and Disease: Molecular Pathology of Calcium

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And Z. , 2004, Discovery of Ca2+ -relevant and differentiation-associated genes downregulated in esophageal squamous cell carcinoma using cDNA microarray. Oncogene. 12; 23(6): 1291–9. R. McCrae, 2000, High affinity binding of beta 2-glycoprotein I to human endothelial cells is mediated by annexin II. J Biol Chem. 275(20):15541–8. M. Waisman, 2003, Phospholipid-associated annexin A2-S100A10 heterotetramer and its subunits: characterization of the interaction with tissue plasminogen activator, plasminogen, and plasmin.

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H. Steinberg, 2005, Association of single nucleotide polymorphisms in klotho with priapism in sickle cell anaemia. Br J Haematol. 128(2):266–72. , 1993, Some consequences of adopting a conditional deterministic causal model in epidemiology. Eur. J. Public Health 3: 204–209. C. Christian, 2006, Evidence for the role of adenosine 5 -triphosphate-binding cassette (ABC)-A1 in the externalization of annexin 1 from pituitary folliculostellate cells and ABCA1-transfected cell models. Endocrinology. 147(7):3219–27.

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